Tagln-2A-DreERT2
品系全名
C57BL/6Smoc-Taglnem1(2A-DreERT2)Smoc
目录号
NM-KI-215038
品系状态
活体
基因信息
基因名
Tagln
品系描述
验证数据
Fig1. DreERT2 mediated recombination in lung of TaglnDreERT2/+;H11tdTomato/+ mouse.
Fig2. DreERT2 mediated recombination in kindey of TaglnDreERT2/+;H11tdTomato/+ mouse.
Fig3. Detection of tdTomato(red) in various tissues of TaglnDreERT2/+;H11tdTomato/+ mouse. Expression tissues include: brain, pituitary gland, thymus, heart, lung, liver, stomach, salivary glands, brown fat, adrenal gland, aorta, kidney, pancreas, small and large intestine, spleen, testis and epididymis, muscle. Tissues that unexpressed include retina. (3-month old) (For more detailed information please contact our technical advisor.)
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Cre-ERT2在无Tamoxifen诱导的情况下,在细胞质内处于无活性状态;当Tamoxifen诱导后,Tamoxifen的代谢产物4-OHT(雌激素类似物)与ERT结合,可使Cre-ERT2进核发挥Cre重组酶活性。
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