Fabp7-CreERT2
品系全名
C57BL/6Smoc-Fabp7em2(Kozak-CreERT2-WPRE-pA)Smoc
目录号
NM-KI-231749
品系状态
精子冻存
基因信息
基因名
Fabp7
品系描述
验证数据
Fig1. CreERT2 mediated recombination in dorsal root ganglia of Fabp7Cre/+; Rosa26tdTomato/+ mouse.
Fig2. Detection of tdTomato(red) in various tissues of AicdaCre/+; Rosa26tdTomato/+.
Tissues expressing tdTomato: brain, spinal cord, eyes, stomach, salivary glands, pituitary, kidneys, pancreas, large intestine, small intestine, spleen, skin, thymus, dorsal root ganglia. Tissues with low expression: lungs, liver, brown fat, adrenal glands, reproductive organs. Tissues without expression: heart, muscles. (51-days old, female) (For more detailed information please contact our technical advisor.)
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Cre-ERT2在无Tamoxifen诱导的情况下，在细胞质内处于无活性状态；当Tamoxifen诱导后，Tamoxifen的代谢产物4-OHT（雌激素类似物）与ERT结合，可使Cre-ERT2进核发挥Cre重组酶活性。
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