Mnx1-2A-CreERT2
品系全名
C57BL/6Smoc-Mnx1em1(2A-CreERT2-WPRE-polyA)Smoc
目录号
NM-KI-200009
品系状态
精子冻存
基因信息
基因名
Mnx1
品系描述
验证数据
Fig1. CreERT2 mediated recombination in spinal cord of Mnx1CreERT2/+; Rosa26tdTomato/+ mouse.
Fig2. Detection of tdTomato(red) in various tissues of Mnx1CreERT2/+; Rosa26tdTomato/+ mouse. Expression tissues include: spinal cord, heart, lungs, stomach, salivary gland, adrenal gland, pancreas, large intestine, small intestine, spleen, testis, muscle, thymus. Scattered cells were expressed in skin.Tissues with no expression: brain, eye, liver, brown adipose tissue, kidney. (7-weeks old, male) (For more detailed information please contact our technical advisor.)
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Cre-ERT2在无Tamoxifen诱导的情况下,在细胞质内处于无活性状态;当Tamoxifen诱导后,Tamoxifen的代谢产物4-OHT(雌激素类似物)与ERT结合,可使Cre-ERT2进核发挥Cre重组酶活性。
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