hCD3EDG

Fig.1 Detection of human CD3E,CD3D,CD3G on T cell surface in HO hCD3EDG mice.

Fig.2 Lymphocyte Lineage Characterization in Blood in Homozygous hCD3EDG Mice.

Fig.3 In Vivo Response with Bispecific T Cell Engager Antibodies in Homozygous hCD3EDG Mice.

Homozygous hCD3EDG mice were engrafted with MC38-hCLDN18.2 to eveluate the in vivo efficacy of anti-CD3×Claudin18.2 bispecific antibody.

Fig.4 In vivo AICD and irAE Assessment of Bispecific T Cell Engager Antibodies in Homzygous hCD3EDG Mice.

Homozygous hCD3EDG mice were engrafted with MC38-hEpCAM to evaluate the AICD and irAE of OKT3 and anti-CD3×EpCAM bispecific antibody in vivo.