Pah-KO
品系全名
C57BL/6Smoc-Pahem1Smoc
目录号
NM-KO-2110565
品系状态
活体
基因信息
基因名
Pah
品系描述
通过敲除Pah基因Exon 2-5，建立Pah基因敲除小鼠模型。
*使用本品系发表的文献需注明: Pah-KO mice (Cat. NO. NM-KO-2110565) were purchased from Shanghai Model Organisms Center, Inc..
疾病预测
苯丙酮尿症
Phenylketonuria
Phenylketonuria
验证数据
Fig1. Characterization of WT C57BL/6 and Pah-KO mice.
(A) The Pah-KO mice showed lower body weights than the WT mice (n=20/group). (B) Summary of blood Phe at various timepoints is shown (n=20/group). (C) Summary of blood Tyr at various timepoints is shown (n=20/group). Note: Data from the third party.
Fig2. Hair coat color in WT C57BL/6 and Pah-KO mice.
Hair coat of the Pah-KO mouse is light brown whereas it is dark brown for the WT C57BL/6 mouse.
Note: Data from the third party.
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