hFcRn(SD)
品系全名
SD-Fcgrtem1(hFCGRT)Smoc
目录号
NR-HU-200002
品系状态
活体
基因信息
基因名
Fcgrt
品系描述
验证数据
Fig1. Expression characterization of hFCRN in hFCRN knockin rat by Western blot.
Abbr. HO, homozygous; WT, wild type.
Fig.2 Blood concentration curve of test articles in hFcRn/hALB dKI rats (NR-HU-233317), which were generated by crossing hFCRN(SD)(NR-HU-200002) with hALB(SD)(NR-HU-200001).
In hFcRn/hALB dKI rats, the half-life time: TA-N434A > TA-YTE > TA. (In cooperation with the third party)
Fig.3 PK study of Keytruda (A) and Cyramza(B) in hALB/hFCRN dKl rat (NR-HU-233317), which were generated by crossing hFCRN(SD)(NR-HU-200002) with hALB(SD)(NR-HU-200001). (n=3/time point/group)
你也可能感兴趣
Cre-ERT2在无Tamoxifen诱导的情况下，在细胞质内处于无活性状态；当Tamoxifen诱导后，Tamoxifen的代谢产物4-OHT（雌激素类似物）与ERT结合，可使Cre-ERT2进核发挥Cre重组酶活性。
查看
