hMC4R-R165W
品系全名
C57BL/6Smoc-Mc4rem1(hMC4R-R165W)Smoc
目录号
NM-HU-233884
品系状态
活体
基因信息
基因名
Mc4r
品系描述
利用同源重组，将小鼠Mc4r基因替换为hMC4R-R165W。
*使用本品系发表的文献需注明: hMC4R-R165W mice (Cat. NO. NM-HU-233884) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig.1 Detection of MC4R expression in brain by RT-PCR. Wild type: only one band at 264 bp with primers F1/R1(mMc4r); Homozygous: only one band at 628 bp with primers F2/R2(hMC4R). Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.2 The sequencing results are consistent with expectations.
Fig.3 Detection of human MC4R expression in brain in hMC4R-R165W mice by WB. Abbr. M, marker; WT, wild type; HO, Homozygous; PC, positive control, HepG2 cells.
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