Fig.1 OVA induced Balb/c mice asthma model. (A) Body weight (B) Body weight change. (*P<0.05, **P<0.01 Vs Group2)
Fig.2 OVA induced Balb/c mice asthma model. (A) Inflammatory cell number in BALF. (B) Eosinophils in BALF. (C) Eosinophils percentage in inflammatory cell. (D) Serum total IgE concentration.
Fig.3 OVA induced asthma model in BALB/c mice. (A) Lung H&E and PAS stain(B) Inflammatory cell infiltration score (C) Bronchial score.
Fig.1 Body weight of HDM induced hIL4/hIL4R mice asthma model (n=6, Data are presented as Mean and ± SEM).
Fig.2 HDM induced hIL4/hIL4R mice asthma model. (A) Inflammatory cell number in BALF. (B) Eosinophils in BALF. (C) Eosinophils percentage in inflammatory cell. (D) Serum total IgE concentration. (n=6, Data are presented as Mean and ± SEM.)
Fig.3 HDM induced hIL4/hIL4R mice asthma model. (A) hIL-4 mRNA expression level. (B) mIL-8 mRNA expression level. (C) mIL-13 mRNA expression level. (D) mIL-6 mRNA expression level. (E) mIL-17a mRNA expression level.
Fig.4 HDM induced hIL-4/hIL-4R mice asthma model. (A) Representative images of H&E staining. (B) Pathology score results. (n=6, Data are presented as Mean and ± SEM.) Magnification, ×5.
Fig.5 HDM induced hIL-4/hIL-4R mice asthma model. (A) Representative images of PAS staining. (B)mucus score. (n=6, Data are presented as Mean and ± SEM.) Magnification, ×10.
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